Leuprorelin: Uses, Side Effects & Brands in Pakistan

Leuprorelin is a GnRH agonist hormone-suppressing injection. It is a prescription medicine used for prostate cancer, endometriosis, fibroids and early puberty. In Pakistan it is available as injections, made by 2 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Leuprorelin works

Leuprorelin is a man-made version of a brain hormone called GnRH. After a brief initial rise, its continuous presence switches off the pituitary gland's signals to the testes or ovaries, so testosterone or oestrogen levels fall. This slows hormone-driven cancers and shrinks hormone-sensitive tissue.

What is Leuprorelin used for?

• Prostate cancer
• Endometriosis
• Fibroids
• Early puberty

Leuprorelin is a long-acting injection used to lower sex hormone levels. It is used to treat hormone-sensitive prostate cancer, endometriosis and uterine fibroids, where it can shrink fibroids before surgery. It is also used to treat early (precocious) puberty in children. It is given by a healthcare professional.

Side effects of Leuprorelin

Most side effects of Leuprorelin come from the lowered hormone levels. They include:

• Hot flushes and sweating
• Reduced sex drive or erection problems
• Tiredness
• Mood changes
• Headache
• Pain or redness at the injection site

Seek urgent medical help if you develop worsening bone pain, difficulty passing urine, weakness or numbness in the legs, chest pain or palpitations.

Precautions and warnings

• In prostate cancer, symptoms can briefly worsen in the first weeks, so your doctor may prescribe another medicine to cover this period.
• Long-term use can thin the bones; your doctor may advise calcium, vitamin D and bone checks.
• Tell your doctor if you have heart disease, heart rhythm problems, diabetes or depression.
• It must not be used in pregnancy; women should use non-hormonal contraception during treatment.
• Tell your doctor about all other medicines you take, particularly those that affect heart rhythm.

Frequently asked questions about Leuprorelin

What is the price of Leuprorelin in Pakistan?

At Medimart, Leuprorelin products currently in stock range from Rs 18,273 to Rs 40,320 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Lucrin 3.75mg Injection at Rs 18,273. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Leuprorelin are available in Pakistan?

Leuprorelin is sold in Pakistan under brand names such as Lucrin (Abbott Laboratories (Pakistan) Ltd) and Lectrum (Novartis Pharma (Pakistan)ltd).

Do I need a prescription for Leuprorelin?

Yes. Leuprorelin is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Leuprorelin be used during pregnancy?

It must not be used in pregnancy; women should use non-hormonal contraception during treatment.

Are all Leuprorelin brands the same?

Brands that contain the same amount of Leuprorelin in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Leuprorelin brands and prices in Pakistan

Medimart lists 4 products containing Leuprorelin from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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