About Kidney DiseaseChronic kidney disease (CKD) is a gradual loss of kidney function. Diabetes and high blood pressure are its most common causes in Pakistan.Early CKD usually has no symptoms. Later it can cause swelling, tiredness, poor appetite, itching and changes in urination. It is detected with blood and urine tests.Medicines used for Kidney DiseaseTreatment aims to slow the disease: controlling blood sugar and blood pressure, and medicines that protect the kidneys such as losartan, irbesartan, other ACE inhibitors or ARBs, and SGLT2 inhibitors such as dapagliflozin and empagliflozin. Avoiding painkillers such as NSAIDs is important.When to see a doctorHave regular kidney tests if you have diabetes or high blood pressure, and always tell doctors and pharmacists about kidney disease before starting a new medicine.This page is for general information only. Many of these medicines need a prescription; please use them only on the advice of a doctor or pharmacist, who can choose the right medicine and dose for you.