About Nerve Pain & NeuropathyNerve pain (neuropathic pain) happens when nerves are damaged or irritated. Common causes include diabetes, shingles, vitamin B12 deficiency and pressure on nerves in the spine.It is often described as burning, shooting, stabbing or electric-shock pain, with numbness, tingling or pins and needles, often in the hands and feet.Medicines used for Nerve Pain & NeuropathyOrdinary painkillers often do not help. Doctors use medicines such as pregabalin, gabapentin, duloxetine or amitriptyline, and vitamin B12 (mecobalamin) when deficiency is a factor. Good blood sugar control is essential in diabetic neuropathy.When to see a doctorSee a doctor for new numbness or weakness, foot wounds that do not heal, or nerve pain that disturbs sleep or daily life.This page is for general information only. Many of these medicines need a prescription; please use them only on the advice of a doctor or pharmacist, who can choose the right medicine and dose for you.