Resmetirom: Uses, Side Effects & Brands in Pakistan

Resmetirom is a liver-targeted thyroid hormone receptor agonist. It is a prescription medicine used for fatty liver disease with fibrosis (MASH/NASH). In Pakistan it is available as tablets, made by 2 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Resmetirom works

Resmetirom activates thyroid hormone beta receptors, which are found mainly in the liver. This increases the liver's ability to break down fat, reducing fat build-up and inflammation and, over time, helping to slow or improve scarring. It is designed to have little effect on the heart or bones.

What is Resmetirom used for?

• Fatty liver disease with fibrosis (MASH/NASH)

Resmetirom is used under specialist care to treat adults with metabolic dysfunction-associated steatohepatitis (MASH, previously called NASH) with moderate to advanced liver scarring but not cirrhosis. It is taken alongside diet and exercise. It is a newer medicine, and longer-term outcome studies are still ongoing.

Side effects of Resmetirom

Side effects of Resmetirom are mostly stomach-related and tend to occur early. They include:

• Diarrhoea
• Nausea
• Itching
• Stomach pain
• Vomiting
• Constipation

Contact your doctor straight away if you develop yellowing of the skin or eyes, dark urine, pain in the upper right abdomen or severe tiredness.

Precautions and warnings

• Your liver tests will be monitored during treatment.
• It interacts with some medicines, including certain statins, clopidogrel and gemfibrozil, so tell your doctor about everything you take.
• Tell your doctor if you have gallbladder disease or thyroid problems.
• There is limited information on use in pregnancy and breastfeeding, so discuss this with your specialist.
• Keep up the diet, exercise and weight loss advice from your doctor, as these remain central to treatment.

Frequently asked questions about Resmetirom

What is the price of Resmetirom in Pakistan?

At Medimart, Resmetirom products currently in stock range from Rs 1,950 to Rs 6,825 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Restiro 80mg Tablets at Rs 1,950. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Resmetirom are available in Pakistan?

Resmetirom is sold in Pakistan under brand names such as Resmirom (Getz Pharma Ltd), Restiro (Horizon Pharmaceutical Pvt Ltd) and Rezkew.

Do I need a prescription for Resmetirom?

Yes. Resmetirom is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Resmetirom be used during pregnancy?

There is limited information on use in pregnancy and breastfeeding, so discuss this with your specialist.

Are all Resmetirom brands the same?

Brands that contain the same amount of Resmetirom in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Resmetirom brands and prices in Pakistan

Medimart lists 4 products containing Resmetirom from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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