Trifluoperazine: Uses, Side Effects & Brands in Pakistan

Trifluoperazine is a phenothiazine antipsychotic. It is a prescription medicine used for schizophrenia, other psychoses, severe anxiety, severe agitation and severe nausea and vomiting. In Pakistan it is available as tablets, made by 2 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Trifluoperazine works

Trifluoperazine blocks dopamine D2 receptors in the brain, calming the overactive dopamine signalling linked to psychotic symptoms. The same action in the brain's vomiting centre explains its anti-sickness effect. Dopamine blockade in the movement areas of the brain is also why it can cause stiffness or tremor.

What is Trifluoperazine used for?

• Schizophrenia
• Other psychoses
• Severe anxiety
• Severe agitation and severe nausea
• Vomiting

Trifluoperazine is used to treat schizophrenia and other psychotic illnesses, helping to reduce symptoms such as hallucinations, delusions and muddled thinking. At low strength it is sometimes used for a short period to control severe anxiety or agitation that has not responded to other treatment, and occasionally for severe nausea and vomiting.

Side effects of Trifluoperazine

Not everyone gets side effects with Trifluoperazine, but the ones reported most often include:

• Drowsiness
• Muscle stiffness or tremor
• Restlessness
• Dry mouth or blurred vision
• Dizziness on standing up
• Weight gain

Seek urgent medical help for a high fever with severe muscle stiffness, sweating or confusion, uncontrollable movements of the face, tongue or limbs, fainting or a fast irregular heartbeat, or yellowing of the skin or eyes.

Precautions and warnings

• Do not stop taking Trifluoperazine suddenly; if it needs to be stopped, your doctor will reduce it gradually.
• Tell your doctor if you have heart disease, epilepsy, Parkinson's disease, glaucoma, liver problems or difficulty passing urine.
• It can cause drowsiness, so avoid alcohol and do not drive or operate machinery until you know how it affects you.
• Older people with dementia have a higher risk of stroke with antipsychotic medicines, so it is used in this group only with great care.
• If you are pregnant or breastfeeding, discuss the risks and benefits with your doctor before using it.

Frequently asked questions about Trifluoperazine

What is the price of Trifluoperazine in Pakistan?

At Medimart, Trifluoperazine products currently in stock range from Rs 15 to Rs 763 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Stelazine 1mg Tablet Tablet at Rs 15. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Trifluoperazine are available in Pakistan?

Trifluoperazine is sold in Pakistan under brand names such as Estezene (Adamjee Pharmaceuticals Ltd.) and Stelazine (Glaxo Smithkline Ltd).

Do I need a prescription for Trifluoperazine?

Yes. Trifluoperazine is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Trifluoperazine be used during pregnancy?

If you are pregnant or breastfeeding, discuss the risks and benefits with your doctor before using it.

Are all Trifluoperazine brands the same?

Brands that contain the same amount of Trifluoperazine in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Trifluoperazine brands and prices in Pakistan

Medimart lists 3 products containing Trifluoperazine from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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