Agomelatine: Uses, Side Effects & Brands in Pakistan

Agomelatine is a melatonergic antidepressant. It is a prescription medicine used for depression. In Pakistan it is available as tablets, made by 3 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Agomelatine works

Agomelatine acts on melatonin receptors, which help set the body clock, and blocks a type of serotonin receptor. Together these effects help restore normal sleep-wake rhythms and increase levels of noradrenaline and dopamine in parts of the brain involved in mood.

What is Agomelatine used for?

• Depression

Agomelatine is used to treat major depression in adults. It may be chosen when sleep disturbance is a prominent part of the depression, or when other antidepressants have caused troublesome side effects such as sexual problems. As with other antidepressants, improvement usually builds up over a couple of weeks or more rather than straight away.

Side effects of Agomelatine

Side effects of Agomelatine are often mild and may settle with time. The more common ones include:

• Headache
• Dizziness
• Drowsiness or difficulty sleeping
• Nausea
• Anxiety
• Back pain

Stop taking it and contact a doctor straight away if you develop yellow skin or eyes, dark urine, pale stools or severe tiredness, or seek urgent help if you have thoughts of harming yourself.

Precautions and warnings

• Agomelatine can affect the liver, so blood tests are needed before you start and regularly during treatment; it is not suitable for people with liver disease.
• Do not take it with fluvoxamine or ciprofloxacin, and tell your doctor about all other medicines you take.
• Avoid alcohol, and do not drive until you know how it affects you.
• Do not stop taking it without speaking to your doctor first.
• It is not recommended during pregnancy or breastfeeding unless your doctor advises it.

Frequently asked questions about Agomelatine

What is the price of Agomelatine in Pakistan?

At Medimart, Agomelatine products currently in stock range from Rs 715 to Rs 1,893 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Modton 25mg Tablets at Rs 715. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Agomelatine are available in Pakistan?

Agomelatine is sold in Pakistan under brand names such as Depurch (Genetics Pharmaceuticals), Modton (Nabiqasim Industries Ltd) and Agoviz (Pharmevo LIMITED.).

Do I need a prescription for Agomelatine?

Yes. Agomelatine is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Agomelatine be used during pregnancy?

It is not recommended during pregnancy or breastfeeding unless your doctor advises it.

Are all Agomelatine brands the same?

Brands that contain the same amount of Agomelatine in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Agomelatine brands and prices in Pakistan

Medimart lists 4 products containing Agomelatine from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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