Isosorbide Dinitrate: Uses, Side Effects & Brands in Pakistan
Isosorbide Dinitrate is a nitrate medicine for angina. It is a prescription medicine used for angina (chest pain) prevention and relief. In Pakistan it is available as tablets and injections, made by 9 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.
How Isosorbide Dinitrate works
Isosorbide dinitrate is converted in the body into nitric oxide, which relaxes and widens blood vessels. Wider veins return less blood to the heart, and wider arteries reduce the resistance it has to pump against, so the heart needs less oxygen and chest pain eases.
What is Isosorbide Dinitrate used for?
- Angina (chest pain) prevention and relief
Isosorbide Dinitrate is used to prevent angina, the chest pain that happens when the heart muscle is not getting enough blood and oxygen. Taken regularly it reduces how often attacks occur, while the sublingual form, placed under the tongue, works within minutes to relieve an attack or can be used before activity known to bring one on. Doctors sometimes also use it, alongside hydralazine, in heart failure.
Side effects of Isosorbide Dinitrate
Headache is very common when starting Isosorbide Dinitrate and often settles after the first week or two. Other common effects include:
- Throbbing headache
- Flushing of the face
- Dizziness or light-headedness, especially on standing
- Fast heartbeat
- Nausea
Call for emergency help if chest pain is not relieved within a few minutes of using it, or if you faint or feel very unwell. Chest pain that keeps coming back or lasts longer than usual may be a heart attack.
Precautions and warnings
- Never take Isosorbide Dinitrate with sildenafil, tadalafil, vardenafil or riociguat, as the combination can cause a dangerous fall in blood pressure.
- Sit down when you use the under-the-tongue form, because it can make you feel faint.
- Do not stop regular treatment suddenly, as this can bring on angina attacks; your doctor will advise how to come off it.
- Alcohol can increase dizziness and the blood pressure-lowering effect, so keep it to a minimum.
- Tell your doctor if you have low blood pressure, severe anaemia, glaucoma, a recent head injury or certain heart valve problems, and if you are pregnant or breastfeeding.
Frequently asked questions about Isosorbide Dinitrate
What is the price of Isosorbide Dinitrate in Pakistan?
At Medimart, Isosorbide Dinitrate products currently in stock range from Rs 2 to Rs 3,157 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Sorbid 10mg Injection at Rs 2. Prices are updated regularly, so the product list on this page always shows the latest price.Which brands of Isosorbide Dinitrate are available in Pakistan?
Isosorbide Dinitrate is sold in Pakistan under brand names such as Isoket (Atco Laboratories Ltd), Isonit (Benson), Isordil (Pfizer Laboratories Ltd), Isdin (Maple Pharmaceuticals Pvt Ltd), Isobaj (Bajwa Pharmaceuticals Pvt Ltd), Sorbid (Aster), Cardiowel (Medicraft) and Isornit (Reko), along with 1 more brands listed below.Do I need a prescription for Isosorbide Dinitrate?
Yes. Isosorbide Dinitrate is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.
Can Isosorbide Dinitrate be used during pregnancy?
Tell your doctor if you have low blood pressure, severe anaemia, glaucoma, a recent head injury or certain heart valve problems, and if you are pregnant or breastfeeding.
Are all Isosorbide Dinitrate brands the same?
Brands that contain the same amount of Isosorbide Dinitrate in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.
Isosorbide Dinitrate brands and prices in Pakistan
Medimart lists 13 products containing Isosorbide Dinitrate from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.
