Pizotifen: Uses, Side Effects & Brands in Pakistan

Pizotifen is a serotonin antagonist migraine preventer. It is a prescription medicine used for migraine prevention and poor appetite. In Pakistan it is available as syrup and tablets, made by 2 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Pizotifen works

Pizotifen blocks the effects of serotonin (5-HT) and histamine. Changes in serotonin activity are thought to play a part in the blood vessel and nerve changes behind migraine, so blocking it helps prevent attacks. Its actions on serotonin and histamine in the brain also increase appetite and cause drowsiness.

What is Pizotifen used for?

• Migraine prevention and poor appetite

Pizotifen is used to reduce how often migraine attacks happen, and in some cases to help prevent cluster headaches. It is a preventive treatment, so it does not stop an attack that has already started and may take several weeks to reach its full effect. Because it can increase appetite, it has also been used in some countries to help people with a poor appetite gain weight.

Side effects of Pizotifen

Drowsiness and increased appetite are the best-known effects of Pizotifen. Other common side effects include:

• Drowsiness
• Increased appetite and weight gain
• Dry mouth
• Dizziness
• Nausea
• Constipation

Seek medical help if you develop severe drowsiness, yellowing of the skin or eyes, a fit, or marked changes in mood such as depression.

Precautions and warnings

• Pizotifen can cause drowsiness, especially at first, so avoid driving and alcohol until you know how it affects you.
• Tell your doctor if you have glaucoma, difficulty passing urine, epilepsy or kidney problems.
• Weight gain is common, so a balanced diet and regular activity can help.
• Do not stop it suddenly after long-term use; your doctor will advise how to reduce it gradually.
• If you are pregnant or breastfeeding, use it only after speaking to your doctor.

Frequently asked questions about Pizotifen

What is the price of Pizotifen in Pakistan?

At Medimart, Pizotifen products currently in stock range from Rs 259 to Rs 845 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Cestonil Syrup 5Mg10ml 120ml at Rs 259. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Pizotifen are available in Pakistan?

Pizotifen is sold in Pakistan under brand names such as Mosegor (Novartis Pharma (Pakistan)ltd) and Cestonil (Raazee Therapeutics Ltd).

Do I need a prescription for Pizotifen?

Yes. Pizotifen is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Pizotifen be used during pregnancy?

If you are pregnant or breastfeeding, use it only after speaking to your doctor.

Are all Pizotifen brands the same?

Brands that contain the same amount of Pizotifen in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Pizotifen brands and prices in Pakistan

Medimart lists 5 products containing Pizotifen from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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