Zoledronic Acid: Uses, Side Effects & Brands in Pakistan

Zoledronic Acid is a bisphosphonate given by infusion. It is a prescription medicine used for osteoporosis, Paget's disease, high calcium in cancer and bone metastases. In Pakistan it is available as injections, made by 3 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Zoledronic Acid works

Zoledronic acid binds tightly to bone and slows the cells that break bone down (osteoclasts). This allows bone-building to catch up, strengthening the bones, reducing the release of calcium into the blood and lowering the risk of fractures and bone pain.

What is Zoledronic Acid used for?

• Osteoporosis
• Paget's disease
• High calcium in cancer
• Bone metastases

Zoledronic Acid is given as a drip into a vein to treat osteoporosis in women after the menopause and in men, reducing the risk of fractures. It is also used for Paget's disease of bone, for high blood calcium caused by cancer, and to protect bones in people whose cancer has spread to the bone.

Side effects of Zoledronic Acid

Side effects of Zoledronic Acid are most common in the first few days after the first infusion. They include:

• Flu-like symptoms such as fever and aches
• Bone, muscle or joint pain
• Headache
• Nausea
• Tiredness

See a doctor if you develop jaw pain, loose teeth or a non-healing mouth sore, new pain in the thigh, hip or groin, eye pain or redness, or muscle cramps and tingling suggesting low calcium.

Precautions and warnings

• It is given as an infusion by healthcare staff, and your kidney function will be checked first; drink plenty of fluids before the infusion.
• Make sure you get enough calcium and vitamin D, as advised by your doctor.
• Have a dental check before starting if possible, keep up good oral hygiene, and tell your dentist you have had it.
• It must not be used during pregnancy or breastfeeding.

Frequently asked questions about Zoledronic Acid

What is the price of Zoledronic Acid in Pakistan?

At Medimart, Zoledronic Acid products currently in stock range from Rs 28,800 to Rs 61,440 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Zoldic 4mg Injection at Rs 28,800. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Zoledronic Acid are available in Pakistan?

Zoledronic Acid is sold in Pakistan under brand names such as Zoldic (CCL Pharmaceuticals Ltd), Zometa (Novartis Pharma (Pakistan)ltd), Aclasta (Novartis Pharma (Pakistan)ltd) and Edonax (S.J. & G. Fazul Ellahie).

Do I need a prescription for Zoledronic Acid?

Yes. Zoledronic Acid is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Zoledronic Acid be used during pregnancy?

It must not be used during pregnancy or breastfeeding.

Are all Zoledronic Acid brands the same?

Brands that contain the same amount of Zoledronic Acid in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Zoledronic Acid brands and prices in Pakistan

Medimart lists 4 products containing Zoledronic Acid from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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