Leflunomide: Uses, Side Effects & Brands in Pakistan

Leflunomide is a disease-modifying antirheumatic drug (DMARD). It is prescribed by rheumatologists in Pakistan, under brands such as Arava and others, to slow joint damage in inflammatory arthritis.

How Leflunomide works

Leflunomide reduces the multiplication of immune cells that drive inflammation in the joints. It takes several weeks to start working.

What is Leflunomide used for?

  • Rheumatoid arthritis
  • Psoriatic arthritis

Side effects of Leflunomide

Not everyone gets side effects. The ones reported more often are:

  • Diarrhoea or nausea
  • Hair thinning
  • Raised blood pressure
  • Rash or itching
  • Changes in liver tests

Get medical help for yellowing of the skin or eyes, a persistent cough or breathlessness, fever, sore throat, unusual bruising, or a severe rash.

Precautions and warnings

  • Leflunomide can cause birth defects and stays in the body for a long time. Women must use reliable contraception, and a special washout treatment may be needed before planning a pregnancy. Men should also discuss family planning with their doctor.
  • Regular blood tests check liver function and blood counts.
  • Avoid alcohol or keep it to a minimum.
  • Avoid live vaccines during treatment.
  • Tell your doctor about liver disease, infections or lung problems.

Frequently asked questions about Leflunomide

How long does leflunomide take to work?

Most people notice benefit after four to six weeks, with further improvement over several months.

Leflunomide brands and prices in Pakistan

Medimart lists 30+ products containing Leflunomide from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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Medical disclaimer: This page is for general information only and does not replace advice from a doctor or pharmacist. Do not start, stop or change any medicine, or its dose, without speaking to a qualified healthcare professional.