Memantine: Uses, Side Effects & Brands in Pakistan

Memantine is a medicine for dementia. It is a prescription medicine used for moderate to severe Alzheimer's disease. In Pakistan it is available as tablets, made by 8 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Memantine works

Memantine blocks NMDA receptors in the brain. In Alzheimer's disease, too much glutamate activity at these receptors is thought to damage nerve cells. By damping down this excess signalling while allowing normal signals through, memantine helps preserve communication between brain cells.

What is Memantine used for?

• Moderate to severe Alzheimer's disease

Memantine is used to treat the symptoms of moderate to severe Alzheimer's disease, such as memory loss, confusion and difficulty with everyday tasks. It may be used on its own or added to a cholinesterase inhibitor such as donepezil. It does not stop the disease, but in some people it can slow the worsening of symptoms for a time and help with daily functioning.

Side effects of Memantine

Memantine is usually well tolerated. Side effects that some people notice include:

• Dizziness
• Headache
• Constipation
• Drowsiness
• Raised blood pressure
• Shortness of breath

See a doctor promptly for fits, sudden worsening confusion or hallucinations, or signs of a blood clot such as leg swelling or chest pain.

Precautions and warnings

• The dose is increased gradually at the start to reduce side effects.
• Tell your doctor about kidney disease, epilepsy, heart problems or high blood pressure.
• Major changes in diet, such as switching to a vegetarian diet, or medicines that change urine acidity can alter memantine levels.
• Avoid using it with amantadine, ketamine or dextromethorphan unless your doctor advises.
• Carers should watch for side effects such as dizziness or drowsiness, and take care with driving and using machinery.

Frequently asked questions about Memantine

What is the price of Memantine in Pakistan?

At Medimart, Memantine products currently in stock range from Rs 506 to Rs 23,227 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Mamgit 10 Tablet 10mg at Rs 506. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Memantine are available in Pakistan?

Memantine is sold in Pakistan under brand names such as Zexa (Arfa & Raj Pharmaceutcals), Afdol (Ali Gohar Pharmaceuticals Ltd), Ebixa (Lundbeck), Memril (Cell Laboratories Ltd), Mamgit (Glitz Pharma), Alzentine (Horizon Pharma), Contine (Amarant Caraway Pharmaceutical) and Rement (High Q International), along with 1 more brands listed below.

Do I need a prescription for Memantine?

Yes. Memantine is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Are all Memantine brands the same?

Brands that contain the same amount of Memantine in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Memantine brands and prices in Pakistan

Medimart lists 9 products containing Memantine from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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