Promethazine: Uses, Side Effects & Brands in Pakistan

Promethazine is a sedating antihistamine. It is a prescription medicine used for allergies, nausea and vomiting, motion sickness, cough and short-term sleep problems. In Pakistan it is available as syrup, tablets and injections, made by 9 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Promethazine works

Promethazine blocks histamine, the chemical released during allergic reactions, which reduces itching, sneezing and swelling. It also acts on the brain's vomiting and balance centres and passes easily into the brain, which explains both its anti-sickness effect and the drowsiness it causes.

What is Promethazine used for?

• Allergies
• Nausea and vomiting
• Motion sickness
• Cough
• Short-term sleep problems

Promethazine is used to relieve allergic conditions such as hay fever, hives, itchy skin and reactions to insect bites. Because it also settles the stomach, it is used for nausea, vomiting and travel sickness. Its sedating effect makes it useful as a short-term aid for sleep problems, and it is included in some cough and cold syrups to calm a troublesome night-time cough.

Side effects of Promethazine

Drowsiness is expected with Promethazine and may last into the next day. Other common effects are:

• Drowsiness
• Dry mouth
• Blurred vision
• Dizziness
• Headache
• Difficulty concentrating

Get medical help for slow or difficult breathing, confusion or hallucinations, fits, uncontrolled movements of the face or body, or yellowing of the skin.

Precautions and warnings

• It must not be given to children under two, as it can dangerously slow their breathing, and it is used with caution in older children.
• Avoid alcohol, and do not drive or use machinery if you feel drowsy, including the morning after taking it at night.
• Tell your doctor if you have glaucoma, prostate problems, difficulty passing urine, epilepsy, asthma or liver disease.
• Do not combine it with other sedating medicines or antihistamines unless a doctor has advised it.
• Ask your doctor before using it in pregnancy or while breastfeeding.

Frequently asked questions about Promethazine

What is the price of Promethazine in Pakistan?

At Medimart, Promethazine products currently in stock range from Rs 26 to Rs 530 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is I-Mazine 5mg|5ml Syrup at Rs 26. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Promethazine are available in Pakistan?

Promethazine is sold in Pakistan under brand names such as I-mazine (Irza), Miprozine (Isis), Phenerzine (Epoch), Prometh (Nova Med), Methazex (Unexo), Phenergan (Sanofi Aventis Pakistan Limited), Pirogan (Alliance) and Etosil (E-lite), along with 1 more brands listed below.

Do I need a prescription for Promethazine?

Yes. Promethazine is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Promethazine be used during pregnancy?

Ask your doctor before using it in pregnancy or while breastfeeding.

Are all Promethazine brands the same?

Brands that contain the same amount of Promethazine in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Promethazine brands and prices in Pakistan

Medimart lists 20+ products containing Promethazine from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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