Misoprostol: Uses, Side Effects & Brands in Pakistan

Misoprostol is a synthetic prostaglandin medicine. It is a prescription medicine used for prevention of NSAID-induced stomach ulcers, stomach and duodenal ulcers, heavy bleeding after childbirth and other obstetric uses under medical supervision. In Pakistan it is available as tablets, made by 6 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Misoprostol works

Misoprostol is a man-made version of prostaglandin E1, a natural substance that lowers stomach acid production and strengthens the protective mucus layer of the stomach. It also makes the muscle of the womb contract and softens the cervix, which is why its use in women is closely controlled.

What is Misoprostol used for?

• Prevention of NSAID-induced stomach ulcers
• Stomach and duodenal ulcers
• Heavy bleeding after childbirth
• Other obstetric uses under medical supervision

Misoprostol is used to protect the stomach lining in people who need to take anti-inflammatory painkillers (NSAIDs) such as diclofenac or naproxen, and to help heal stomach and duodenal ulcers. In obstetrics and gynaecology it is used only under direct specialist supervision, for example to help prevent or control heavy bleeding after childbirth. It must never be used during pregnancy without a doctor's direction.

Side effects of Misoprostol

Misoprostol can cause stomach-related side effects, especially in the first few days. The more common ones include:

• Diarrhoea
• Stomach cramps or pain
• Nausea
• Wind and bloating
• Headache

Get urgent medical help for heavy vaginal bleeding, severe abdominal pain, fever, or signs of an allergic reaction such as swelling of the face or difficulty breathing.

Precautions and warnings

• Misoprostol can cause miscarriage and birth defects, so it must not be taken during pregnancy except under direct medical supervision.
• Women who could become pregnant should use reliable contraception while taking it for stomach protection.
• Taking it with food can help reduce diarrhoea, and antacids containing magnesium should be avoided as they can make diarrhoea worse.
• Tell your doctor if you have inflammatory bowel disease, heart or blood vessel disease, or any condition where dehydration could be dangerous.
• If you are breastfeeding, check with your doctor before using it.

Frequently asked questions about Misoprostol

What is the price of Misoprostol in Pakistan?

At Medimart, Misoprostol products currently in stock range from Rs 234 to Rs 289 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Miso 200mcg Tablets at Rs 234. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Misoprostol are available in Pakistan?

Misoprostol is sold in Pakistan under brand names such as Prosotec (Atco Laboratories Ltd), Miso (A & J Company), Mite (Genix Pharma Ltd), Breeky (Sami Pharma Ltd), Cytolol (A & J Company) and Misopros (Platinum Pharmaceuticals Ltd).

Do I need a prescription for Misoprostol?

Yes. Misoprostol is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Misoprostol be used during pregnancy?

Misoprostol can cause miscarriage and birth defects, so it must not be taken during pregnancy except under direct medical supervision.

Are all Misoprostol brands the same?

Brands that contain the same amount of Misoprostol in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Misoprostol brands and prices in Pakistan

Medimart lists 9 products containing Misoprostol from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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