Clomipramine: Uses, Side Effects & Brands in Pakistan

Clomipramine is a tricyclic antidepressant. It is a prescription medicine used for depression, OCD, panic disorder, phobias and cataplexy in narcolepsy. In Pakistan it is available as tablets, made by 5 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Clomipramine works

Clomipramine blocks the reabsorption of serotonin and, to a lesser extent, noradrenaline into nerve cells, increasing the amount of these mood-regulating chemicals available in the brain. Its strong effect on serotonin is thought to explain its benefit in OCD.

What is Clomipramine used for?

• Depression
• OCD
• Panic disorder
• Phobias
• Cataplexy in narcolepsy

Clomipramine is used to treat depression and is particularly useful for obsessive-compulsive disorder (OCD), where it can reduce intrusive thoughts and repetitive behaviours. It is also prescribed for panic disorder and phobias, and occasionally for sudden muscle weakness (cataplexy) in narcolepsy. Benefits usually take a few weeks to appear, so it is important to keep taking it as prescribed.

Side effects of Clomipramine

Especially in the first few weeks, Clomipramine may cause:

• Dry mouth
• Drowsiness or tiredness
• Constipation
• Dizziness
• Sweating
• Blurred vision

Seek help immediately if you have thoughts of harming yourself, a fast or irregular heartbeat, a fit, or a high fever with stiffness, agitation and confusion. Difficulty passing urine also needs prompt medical advice.

Precautions and warnings

• Tell your doctor if you have heart disease or a recent heart attack, epilepsy, glaucoma, an enlarged prostate, liver disease or bipolar disorder.
• Do not take it with MAOI antidepressants, and check with your doctor before combining it with other medicines that raise serotonin, such as SSRIs or tramadol.
• Do not stop it suddenly; your doctor will reduce the dose gradually to avoid withdrawal symptoms.
• Avoid alcohol and do not drive or operate machinery until you know how it affects you.
• An overdose of tricyclic antidepressants is dangerous, so store it safely, and talk to your doctor if you are pregnant or breastfeeding.

Frequently asked questions about Clomipramine

What is the price of Clomipramine in Pakistan?

At Medimart, Clomipramine products currently in stock range from Rs 671 to Rs 1,028 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Clomipril 75 mg Tablets at Rs 671. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Clomipramine are available in Pakistan?

Clomipramine is sold in Pakistan under brand names such as Clomfranil (Sandoz Pharma), Denla (Semos Pharmaceuticals Ltd), Clomipril (Libra Pharmaceutical Ltd) and Clopra (Medera Pharmaceutical Ltd).

Do I need a prescription for Clomipramine?

Yes. Clomipramine is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Clomipramine be used during pregnancy?

An overdose of tricyclic antidepressants is dangerous, so store it safely, and talk to your doctor if you are pregnant or breastfeeding.

Are all Clomipramine brands the same?

Brands that contain the same amount of Clomipramine in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Clomipramine brands and prices in Pakistan

Medimart lists 6 products containing Clomipramine from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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