Hydroquinone + Tretinoin + Fluocinolone: Uses, Side Effects & Brands in Pakistan

Hydroquinone + Tretinoin + Fluocinolone is a triple-combination skin-lightening cream. It is a prescription medicine used for melasma. In Pakistan it is available as cream, made by 6 different manufacturers. On this page you can read how it works, its common side effects and precautions, and compare the brands and prices available at Medimart.

How Hydroquinone + Tretinoin + Fluocinolone works

Hydroquinone reduces melanin production by blocking tyrosinase, the enzyme pigment cells use to make it. Tretinoin speeds up skin cell turnover, so pigmented cells are shed faster and hydroquinone penetrates better. Fluocinolone acetonide is a corticosteroid that calms the irritation the other two ingredients can cause.

What is Hydroquinone + Tretinoin + Fluocinolone used for?

  • Melasma

Hydroquinone + Tretinoin + Fluocinolone cream is used for short courses to treat moderate to severe melasma of the face, the patchy brown or grey-brown pigmentation often triggered by sun exposure, pregnancy or hormonal contraception. It lightens the dark patches gradually over several weeks. It is not intended for long-term maintenance, and strict sun protection is needed both during and after treatment to help stop melasma returning.

Side effects of Hydroquinone + Tretinoin + Fluocinolone

Skin reactions are common with Hydroquinone + Tretinoin + Fluocinolone, especially in the early weeks, and include:

  • Redness
  • Peeling or dryness
  • Burning or stinging
  • Itching
  • Acne-like spots
  • Increased sensitivity to sunlight

Stop using it and contact your doctor if you develop severe redness, blistering, swelling or a crusting rash, or if the skin darkens to a bluish-black colour (ochronosis).

Precautions and warnings

  • Hydroquinone + Tretinoin + Fluocinolone is meant for short-term use only, generally up to about eight weeks, because prolonged use of the steroid can thin the skin and prolonged hydroquinone use can cause ochronosis.
  • Apply a broad-spectrum sunscreen every day and avoid strong sunlight, as tretinoin makes skin more sensitive to the sun and sun exposure worsens melasma.
  • Do not use it during pregnancy or while trying to conceive, and speak to your doctor if you are breastfeeding.
  • Keep it away from the eyes, lips, nostrils and broken or eczema-affected skin, and avoid harsh soaps, peels or other irritating products at the same time.
  • Tell your doctor if you have a sulfite allergy, as some formulations contain sodium metabisulfite.

Frequently asked questions about Hydroquinone + Tretinoin + Fluocinolone

What is the price of Hydroquinone + Tretinoin + Fluocinolone in Pakistan?

At Medimart, Hydroquinone + Tretinoin + Fluocinolone products currently in stock range from Rs 197 to Rs 631 per pack, depending on the brand, strength and pack size. The lowest-priced option right now is Hydroquin Plus Cream at Rs 197. Prices are updated regularly, so the product list on this page always shows the latest price.

Which brands of Hydroquinone + Tretinoin + Fluocinolone are available in Pakistan?

Hydroquinone + Tretinoin + Fluocinolone is sold in Pakistan under brand names such as Hyderquin (Atco Laboratories Ltd), Siton (Shaigan Pharmaceuticals Ltd), Tri (Brookes Pharmaceutical Labs (Pak) Ltd), Flytro (Tabros Pharma), Trimelasin (Valor Pharmaceuticals), Lazma (Bio Pharma), Beautic (Fazal Dins Pharma Plus) and Hydroquin (Atco Laboratories Ltd).

Do I need a prescription for Hydroquinone + Tretinoin + Fluocinolone?

Yes. Hydroquinone + Tretinoin + Fluocinolone is a prescription medicine in Pakistan. Use it only when a doctor has prescribed it, at the dose and for the time they advise.

Can Hydroquinone + Tretinoin + Fluocinolone be used during pregnancy?

Do not use it during pregnancy or while trying to conceive, and speak to your doctor if you are breastfeeding.

Are all Hydroquinone + Tretinoin + Fluocinolone brands the same?

Brands that contain the same amount of Hydroquinone + Tretinoin + Fluocinolone in the same form are expected to work in the same way, although inactive ingredients, pack sizes and prices differ. Ask your doctor or pharmacist before switching from one brand to another.

Hydroquinone + Tretinoin + Fluocinolone brands and prices in Pakistan

Medimart lists 9 products containing Hydroquinone + Tretinoin + Fluocinolone from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.

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Medical disclaimer: This page is for general information only and does not replace advice from a doctor or pharmacist. Do not start, stop or change any medicine, or its dose, without speaking to a qualified healthcare professional.