Sitagliptin + Metformin: Uses, Side Effects & Brands in Pakistan
Sitagliptin with metformin combines two type 2 diabetes medicines in one tablet. It is prescribed in Pakistan, under brands such as Janumet and many local brands, when metformin alone does not control blood sugar.
How Sitagliptin + Metformin works
Sitagliptin is a DPP-4 inhibitor that helps the body release more insulin after meals. Metformin reduces the sugar the liver releases. Together they lower blood sugar with a low risk of hypoglycaemia.
What is Sitagliptin + Metformin used for?
- Type 2 diabetes not controlled by metformin alone
- Replacing separate sitagliptin and metformin tablets with one tablet
- With other medicines such as insulin or a sulfonylurea when needed
Side effects of Sitagliptin + Metformin
Not everyone gets side effects. The ones reported more often are:
- Nausea, diarrhoea or stomach upset
- Headache
- Cold-like symptoms
- Low blood sugar when combined with insulin or sulfonylureas
Get urgent help for severe stomach pain spreading to the back (a sign of pancreatitis), or for severe weakness, muscle pain and difficulty breathing (rare lactic acidosis from metformin). Also report severe joint pain or blistering skin.
Precautions and warnings
- Your doctor will check kidney function regularly.
- You may need to pause it before surgery or a scan with contrast dye.
- Avoid heavy alcohol use.
- Contact your doctor if you are dehydrated from vomiting or diarrhoea.
- It is not used for type 1 diabetes.
Frequently asked questions about Sitagliptin + Metformin
Does sitagliptin with metformin cause weight gain?
Usually not. Both medicines are generally weight-neutral.
Sitagliptin + Metformin brands and prices in Pakistan
Medimart lists 40+ products containing Sitagliptin + Metformin from different manufacturers. Compare strengths, pack sizes and prices below and order online with cash on delivery.
